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Two or three clusters, read side by side across sectors, research, companies, capital, infrastructure, government designations and UKIZ relevance. There is no score and no ranking: British clusters are different from one another, not better or worse than one another.

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Side by side

Dimension	Teesside & the HumberNorth East / Yorkshire and the Humber	Liverpool City RegionNorth West	ManchesterNorth West
Sectors	Clean Energy, Advanced Manufacturing, Advanced Materials Supporting: Digital Technologies, AgriTech & FoodTech	Life Sciences, Engineering Biology, Advanced Materials Supporting: Digital Technologies, Clean Energy, Creative Industries	Advanced Materials, Life Sciences, Digital Technologies, Creative Industries Supporting: Artificial Intelligence, Advanced Manufacturing, Financial Technology, Engineering Biology
Research	Not recorded on the map.	University of Liverpool Liverpool School of Tropical Medicine	The University of Manchester Manchester Metropolitan University National Graphene Institute Greater Manchester health innovation partnership
Companies	Not recorded on the map.	Not recorded on the map.	Not recorded on the map.
Infrastructure	Centre for Process Innovation Process innovation and biologics scale-up facilities, port capacity and grid-connected industrial land.	Not recorded on the map. University research institutes, automated chemistry facilities and port and logistics assets.	MediaCity Advanced manufacturing Catapult capability, North West National materials and graphene facilities, teaching hospitals and clinical research capability, and a major broadcast production estate.
Capital	Infrastructure capital, corporate investment and public programmes; almost no local venture base.	A modest local investor base; public and charitable research funding dominate.	A growing regional investor base and northern funds, with growth rounds usually led from London.
Government programmes	Teesside Freeport — Freeports Humber Freeport — Freeports	Liverpool City Region Freeport — Freeports	No place-based designation recorded.
What exists	The largest concentration of industrial decarbonisation activity in the UK: hydrogen, carbon capture, process manufacturing, biologics scale-up capability and two Freeports with substantial serviced industrial land.	Infection and tropical medicine research of international standing, materials chemistry and automated discovery, a large port and a Freeport designation.	Advanced materials research including graphene and 2D materials, a large health innovation base built on hospitals and universities, a substantial digital and cyber economy, and the biggest broadcast and creative cluster outside London.
What's missing · UKIZ interpretation	Skills pipelines and company formation. The land, power and permits exist; the innovation companies and the technical workforce to fill them do not yet exist at the same scale.	Translation capacity: strong discovery science with limited local scale-up manufacturing and limited early-stage capital to hold companies in the city region.	The step from materials discovery to volume production, and a growth capital base proportionate to the research output. Health data at population scale is under-used by industry.
What could connect · UKIZ interpretation	Industrial land and process scale-up capability connected to research clusters elsewhere that have technologies without a place to build them — a national scale-up site rather than a regional one.	Infection and biologics research connected to North West and Teesside biomanufacturing capacity, with the port used for export rather than only import.	Materials research connected to Sheffield and Midlands manufacturing, and health innovation connected to Leeds health data capability — a corridor rather than three separate cities.
UKIZ relevance	This is where Britain either builds an energy supply chain or imports one. The proposed Teesside & Humber mission is explicitly about retained industrial capability.	Discovery and manufacture sit unusually close together here. The proposed Manchester mission treats the North West as one health and biomanufacturing geography.	Manchester has scale in four different economies that rarely commission from each other. The proposed zone concentrates on connecting health, materials, digital and creative capability around shared missions.
Last verified	15 August 2026	15 August 2026	15 August 2026

Proposed by UKIZ · independent · not a government designation

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